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Biographical SketchOriginally from Bay Village, Ohio, Ms. King received her BA from Ohio University, Athens, Ohio in 1970 and her post baccalaureate degree in physical therapy from The Ohio State University in 1974. She has been a staff physical therapist at Children’s Hospital in Columbus and was recruited to help form the first pediatric unit at Dodd Hall, OSU’s nationally recognized rehabilitation hospital. Research SummaryMs. King has co-authored numerous articles in the neuromuscular field. She has extensive experience as an evaluator in clinical research trials of Duchenne, facioscapulohumeral, and limb girdle muscular dystrophies, motor neuron diseases including ALS, Kennedy’s disease and spinal muscular atrophy, peripheral neuropathies (Charcot MarieTooth, chronic inflammatory demyelinating polyneuropathy), inflammatory myopathies (inclusion body myositis, dermatomyositis) and myasthenia gravis. Her particular interests include documenting the natural history of neuromuscular diseases, the methodologies of strength and functional testing, and training health professionals in the same. She is a member of the American Physical Therapy Association and the American Academy of Neurology. Publications (Selected)Florence JM, Pandya S, King WM, Signore L, Wentzell M, Province M, and the CIDD Group: Clinical Trials in Duchenne muscular dystrophy: III Standardization and reliability of evaluation procedures. Physical Therapy 64: 41-45, 1984. Pandya S, Florence JM, King WM, Robison JD, Oxman M, Province MA: Reliability of goniometric measurements in patients with Duchenne muscular dystrophy. Physical Therapy 65: 1339-1342, 1985. Brooke MH, Fenichel GM, Griggs RC, Mendell JR, Moxley RT, Florence JM, King WM, Pandya S, Robison JD, Schierbecker J, Signore LC, Miller JP: Duchenne muscular dystrophy: patterns of clinical progression and effects of supportive therapy. Neurology 39: 475-481, 1989. Mendell JR, Moxley RT, Griggs RC, Brooke MH, Fenichel GM, Miller JP, King WM, Pandya S, Florence JM, Schierbecker J, Robison JD: Randomized, double-blind six month trial of prednisone in Duchenne’s muscular dystrophy. New England Journal of Medicine 320: 1592-1597, 1989. Burnett CN, Betts EF, King WM: Reliability of isokinetic measurements of hip muscle torque in young boys. Physical Therapy 70: 244-249, 1990. Fenichel GM, Florence JM, Pestronk A, Mendell JR, Moxley III RT, Griggs RC, Brooke MH, Miller JP, Robison JD, King WM, Signore LC, Pandya S, Schierbecker J, Wilson B: Long-term benefit from prednisone therapy in Duchenne muscular dystrophy. Neurology 41: 1874-1877, 1991. Fenichel GM, Mendell JR, Moxley RT, Griggs RC, Brooke MH, Miller JP, Pestronk A, King WM, Robison JD, Pandya S, Florence JM, Schierbecker J: A comparison of daily and alternate –day prednisone therapy in the treatment of Duchenne muscular dystrophy. Archives of Neurology 48: 575-579, 1991. Florence JM, Pandya S, King WM, Robison JD, Baty J, Miller JP, and Schierbecker J: Interrater reliability of manual muscle grades in Duchenne muscular dystrophy. Physical Therapy 72: 115-126, 1992. Personius K, Pandya S, King WM, Tawil R, McDermott M, and the FSH-DY group: Facioscapulohumeral dystrophy natural history study: standardization of testing procedures and reliability of measurements. Physical Therapy 74: 253-263, 1994. Tawil R, McDermott MP, Mendell JR, Kissel JT, King WM, Griggs RC, and the FSH-DY Group: Facioscapulohumeral muscular dystrophy (FSHD): Design of natural history study and results of baseline testing. Neurology 44: 442-446, 1994. Mendell JR, Kissel JT, Amato AA, King WM, Signore LC, Prior TW, Sahenk Z, Benson S, McAndrew PE, Rice R, Nagara H, Stephens R, Lantry L, Morris GE, and Burghes AHM: Myoblast transfer in the treatment of Duchenne’s muscular dystrophy. The New England Journal of Medicine 333: 832-838, 1995. The FSH-DY Group: A prospective, quantitative study of the natural history of facioscapulohumeral muscular dystrophy (FSHD): implications for therapeutic trials. Neurology 48: 38-46, 1997. Tawil R, McDermott MP, Pandya S, King WM, Kissel JT, Mendell JR, Griggs RC, and the FSH-DY Group: A pilot trial of prednisone in facioscapulohumeral muscular dystrophy (FSHD). Neurology 48: 46-49, 1997. McDermott MP, Tawil R, Natarajan MA, Forrester J, Figlewicz D, Griggs RC, Pandya S, Kissel J, King WM, Mendell JR, and the FSH-DY Group: Distinct Patterns of Weakness in Facioscapulohumeral Muscular Dystrophy. Annals of Neurology 42: 450, 1997. Mendell JR, Barohn RJ, Freimer ML, King WM, Kissel JT, and the Working Group on Peripheral Neuropathy: Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. Neurology 56:445-449, 2001. Fenichel GM, Griggs RC, Kissel JT, Kramer TI, Mendell JR, Moxley RT, Pestronk A, Sheng K, Florence J, King WM, Pandya S, Robison VD, Wang H: A randomized efficacy and safety trial of oxandrolone in the treatment of Duchenne dystrophy. Neurology 56:1075-1079, 2001. Kissel JT, McDermott MP, Mendell JR, King WM, Pandya S, Griggs RC, Tawil R, and the FSH-DY Group: Randomized, double-blind, placebo-controlled trial of albuterol in facioscapulohumeral dystrophy. Neurology 57:1434-1440, 2001. The Muscle Study Group: Randomized, pilot trial of ßINF1a (Avonex) in patients with inclusion body myositis. Neurology 57:1566-1570, 2001. Wicklund MP, Moore SA, Campbell KP, Matthews K, Wall CA, King WM, and the LGMD Study Group: Molecular and clinical characterization of individuals with limb-girdle muscular dystrophy. Neurology 56: Number 8, supplement 3, A211, 2001. Serrano C, Wall CA, Moore SA, King WM, Campbell K, Mendell JR: Gentamicin treatment for muscular dystrophy patients with stop codon mutations. Neurology 56: Number 8, supplement 3, A79, 2001. Sorenson EJ, King WM, Newman D, and the Great Lakes ALS Study Group: A comparison of muscle strength testing techniques in amyotrophic lateral sclerosis. Neurology 2003, in press. King WM, Ruttencutter RE, Hoyle CJ, et al: Orthopedic effects of steroid-treatment in Duchenne dystrophy. Neurology 60:A234 March 2003 (Suppl 1). Contact389 McCampbell Hall Tel: (614) 292-1234 |
